Functional mapping of central noradrenergic neurons in the control of breathing
Several respiratory pathophysiologies including SIDS, Rett syndrome, and CCHS feature both disordered breathing and are associated with brainstem noradrenergic system (NA) abnormalities.
Screening for genes and pre-natal exposures in Sudden Infant Death Syndrome
Sudden Infant Death Syndrome claims the lives of as many as 14 infants each day in the United States alone. SIDS is typically defined as the death of an otherwise healthy infant, which leave few clues to understand how this devastating disease may occur.
Mapping the innervation of the knee joint to understand pain pathways
Treatment of pain in osteoarthritis (OA) often relies on opiates which can contribute to the current opiate epidemic that claims more than 70,000 lives annually. We are working to map the neural innervation of the knee to better understand how pain develops during OA for better treatments.
