We study how neurons and glia come together to create networks that underly our physiology and behavior to better understand pathophysiologies, behavioral disorders, and neurodegenerative diseases.
Current Research Projects
Functional mapping of central noradrenergic neurons in the control of breathing
Several respiratory pathophysiologies including SIDS, Rett syndrome, and CCHS feature both disordered breathing and are associated with brainstem noradrenergic system (NA) abnormalities.
Screening for genes and pre-natal exposures in Sudden Infant Death Syndrome
Sudden Infant Death Syndrome claims the lives of as many as 14 infants each day in the United States alone. SIDS is typically defined as the death of an otherwise healthy infant, which leave few clues to understand how this devastating disease may occur.
COVID-19 and the effects of SARS-CoV-2 infection on the nervous system
The current pandemic has revealed a multitude neurological sequelae in both the acute phase of infection and long lasting after the infection has cleared (Long COVID). It remains unclear whether these effects are the result of direct nervous system infection or stem from indirect inflammatory effects, neuro-vascular damage, or PAMPS/DAMPS (Pathogen associated molecular patterns or Damage associated molecular patterns) crossing the blood brain barrier.