The lab recently submitted an RO1 grant with the aim of utilizing a recently developed automated closed loop neonate respiratory assessment platform to screen mouse mutants from the BCM KOMP effort. KOMP, or the Knockout Mouse Project is an international effort to mutate and broadly phenotype every gene in the mouse genome. The grant will leverage an array of our newly developed platforms to screen KOMP mutants for phenotypes in protective neonate respiratory reflexes that may be disrupted in Sudden…
The lab successfully renewed their first R01 (on the first submission!) and was recently awarded a $3 Million NIH Grant to continue their study of the central noradrenergic system in breathing and its potential roles in SIDS and Rett Syndrome for another five years. The first grant has a been a resounding success by establishing a foundational map of central noradrenergic circuit organization in breathing control, identifying noradrenergic neural correlates as potential therapeutic targets in Rett Syndrome, and establishing a novel role of…